About Spermidine is an educational resource created by scientists to explore the cutting-edge research behind spermidine.
Spermidine ameliorates colitis via induction of anti-inflammatory macrophages and prevention of intestinal dysbiosis
A systematic exploration reveals the potential of spermidine for hypopigmentation treatment through the stabilization of melanogenesis-associated proteins
Non-linear association between serum spermidine and mild cognitive impairment: Results from a cross-sectional and longitudinal study
Elevated spermidine serum levels in mild cognitive impairment, a potential biomarker of progression to Alzheimer dementia, a pilot study
Elevation of Serum Spermidine in Obese Patients: Results from a Cross-Sectional and Follow-Up Study
Effects of Spermidine on Gut Microbiota Modulation in Experimental Abdominal Aortic Aneurysm Mice
Spermidine-mediated hypusination of translation factor EIF5A improves mitochondrial fatty acid oxidation and prevents non-alcoholic steatohepatitis progression
Spermidine activates mitochondrial trifunctional protein and improves antitumor immunity in mice
Protective Role of Spermidine in Colitis and Colon Carcinogenesis
Effects of Spermidine Supplementation on Cognition and Biomarkers in Older Adults With Subjective Cognitive Decline
The effect of spermidine on autoimmunity and beta cell function in NOD mice
Spermidine reduces neuroinflammation and soluble amyloid beta in an Alzheimer’s disease mouse model
Mechanisms of spermidine-induced autophagy and geroprotection
Spermidine supplementation influences mitochondrial number and morphology in the heart of aged mice
Spermidine improves gut barrier integrity and gut microbiota function in diet-induced obese mice
Spermidine Rescues Bioenergetic and Mitophagy Deficits Induced by Disease-Associated Tau Protein
Spermidine suppresses the activation of hepatic stellate cells to cure liver fibrosis through autophagy activator MAP1S
Effects of Spermidine on Cell Proliferation, Migration, and Inflammatory Response in Porcine (pig) Enterocytes
Spermidine induces cytoprotective autophagy of female germline stem cells in vitro and ameliorates aging caused by oxidative stress through upregulated sequestosome-1/p62 expression
Autophagy is required for oogenesis and plays a critical role in response to aging caused by oxidative stress. However, there have been no reports on regulation of cytoprotective autophagy in female germline stem cells (FGSCs) in response to aging caused by oxidative stress until now.
Spermidine Protects Telomere Length
Although ageing causes cellular deterioration, a recent study in 2021 using older mice has found that spermidine supplements prevent age-related telomere shortening, indicating that spermidine has a cardioprotective effect and prevents the development of age-related disease.